The pharmaceutical industry has especially used building blocks intensively since the 1990s as these are used for researching pharma-active agents. Building blocks often function like “libraries”, i.e. as a carefully chosen selection of a few hundred to thousand building blocks for screening new active agents.
Building blocks are synthesis building blocks, which are used to produce organic molecules. Building blocks most often have one or multiple functional groups. Moreover, they are linked to other synthesis building blocks: Heterocyclic core structures such as pyridine, pyrrolidine or thiophene can be substituted with functional groups such as alcohols, aldehydes, carbonic acid, amines, amides, sulphonic acids, boronic acids, anhydrides, esters, nitriles, nitro compounds, diazo compounds, cyanates, isocyanates, alkenes, alkines or fluorine-containing groups.